Floyd Reifer has replaced Richard Pybus as interim head coach just seven weeks before the start of the World Cup, Cricket West Indies announced.
Robert Haynes has replaced Courtney Browne as interim head of selectors, while the entire selection panel has also been dismissed.
"We are confident that in Mr Haynes we have found an interim chairman who shares the philosophy of inclusiveness and shares our selection policy," Cricket West Indies (CWI) president Ricky Skerritt said.
"(Reifer) has lived the same principles of West Indian excellence that we now insist must prevail in our cricket."
They kick-off their World Cup campaign against Pakistan at Trent Bridge on May 31.
The appointment of Englishman Pybus had been met with criticism, including from former captain Darren Sammy, who blamed him for causing the West Indies squad to strike on the 2016 India tour while the director of cricket.
"Moses led God's children out of Egypt and a 40days journey took them 40years because of stubbornness. The 2019 worldcup will be 40years since WI won," tweeted Sammy in January.
The change of management could potentially open the way for star players to return to the team, with the likes of Dwayne Bravo, Kieron Pollard and Andre Russell playing almost exclusively franchise T20 cricket.
Cricket West Indies president Dave Cameron was ousted from his post last month with Ricky Skerritt taking over as president.