Chris Gayle, Andre Russell and Evin Lewis were named in the West Indies' 2019 ODI World Cup squad announced on Wednesday, while Kieron Pollard was among those left out of the final 15.
Gayle returned to the Windies ODI side in their 2-2 series draw against England earlier this year. Russell, who did not feature against England due to injuries, has mainly featured as a batsman in T20 leagues over the past year.
"I spoke with Andre about four days ago and he assured me that he'll be OK for the World Cup," said West Indies chief selector Robert Haynes. "He just has a couple of niggling injuries."
Interim coach Floyd Reifer, who replaced the sacked Richard Pybus earlier this month, said Russell was in the squad mainly as a batsman.
"Looking at the IPL, he's been scoring a lot of runs, so we're going to use him as a batting allrounder," said Reifer.
"We'll have to manage his injuries between games."
Despite the Windies relaxing their rules regarding international players needing to play in their domestic competitions to qualify for selection, there were no places in the squad for Pollard or Sunil Narine. The duo is currently featuring in the IPL for Mumbai Indians and Kolkata Knights Riders respectively. The duo last represented the West Indies back in 2016.
Narine is suffering from a finger injury and does not feel able to play the longer limited-overs format.
"We had a lot of dialogue with Sunil and he assured us he would love to be playing for the West Indies, but he has a very sore finger," added Haynes.
"He's getting treatment after every IPL game, and he cannot bowl 10 overs and is struggling to bowl four."
Another big name to miss out is Marlon Samuels.
Nicholas Pooran and Shimron Hetmyer were included, as was Evin Lewis..
Lewis is likely to partner Gayle, who is just 252 runs away from breaking Brian Lara's all-time ODI West Indies record.
The Windies get their campaign underway against Pakistan at Trent Bridge on May 31.
They can make changes to their squad until May 23, but director of cricket Jimmy Adams said there were no such plans.
Windies will play a tri-series with Bangladesh and Ireland in Dublin ahead of the World Cup.
Jason Holder (c), Andre Russell, Ashley Nurse, Carlos Brathwaite, Chris Gayle, Darren Bravo, Evin Lewis, Fabian Allen, Kemar Roach, Nicholas Pooran (wk), Oshane Thomas, Shai Hope (wk), Shannon Gabriel, Sheldon Cottrell, Shimron Hetmyer