James Anderson has been ruled out of England's four-day Test against Ireland with injury to his right calf.
Anderson sustained the injury during the country match for his side Lancashire against Durham which had left him doubtful for the start of the summer.
"Jimmy will continue to be assessed" ahead of the first Ashes Test at Edgbaston on August 1, said ECB in a statement on Tuesday.
England Chief selector Ed Smith had earlier expressed his concerns as he didn’t want to risk Anderson ahead of the all-important Ashes series.
England’s fast bowling stocks are currently nursing injuries with Mark Wood and Jofra Archer still recovering from side strains picked up during the World Cup.
Anderson, with 575 wickets to his name, holds the record for the most Test wickets by a fast bowler.
Sri Lankan off-spinner Muttiah Muralitharan leads the table with 800 wickets, ahead of Australia's Shane Warne (708) and India's Anil Kumble (619).