Aiden Markram will not be available for the third and final Test against India after he sustained a wrist injury during the previous game in Pune.
Markram reportedly "lashed out a solid object" following his dismissal for nought in the second innings and fractured his wrist bones.
"The medical team has, therefore, ruled him out of the next Test match against India. Arrangements have been made for him to see a specialist on his return to South Africa for further management of the injury," South Africa team doctor Hashendra Ramjee said in a statement.
Markram has been having a torrid time with the bat failing to put on substantial scores in the ongoing three-match series in India.
He registered a pair of ducks in the second Test, which India won by an innings and 137 runs to claim a record 11th series victory at home.
Markram showed remorse over the unfortunate incident and took full responsibility for his actions.
“It’s sad to be going home on this note and I completely understand what I’ve done wrong and take full accountability for it.
"It’s unacceptable in a Proteas environment and to let the team down is what hurts me the most. I’ve learned a lot from this and the other players I’m sure, have learned from it as well," he said.
South Africa do not have another specialist opening batsman in the squad who could replace Markram and will have to thus settle on a makeshift player to partner Dean Elgar at the top.
"We understand in sport that emotions run high and sometimes the frustration gets the better of you as it did for me, but like I said, it’s no excuse," Markram added as he rendered an apology to his teammates and the management.
Earlier this week, Australia all-rounder Mitchell Marsh was involved in a similar incident that saw him fracture his hand after punching the dressing room wall in frustration.