Alex Carey will be making a case for Test selection as he has been entrusted with captaincy duties for the three-day game against Pakistan ahead of the two-match series.
Carey grabbed the headlines with breathtaking performances during the World Cup earlier this year but could not break into the Australia Test side for the Ashes with the selectors opting for Matthew Wade as the back-up wicketkeeper.
The 28-year-old, who is vice-captain of Australia's white-ball teams, does not boast highly impressive numbers in first-class cricket with an average of 32.48 across 33 games though he recently struck a century against Victoria in the Sheffield Shield.
Usman Khawaja has also been named in the Australia A line-up for the tour game to be held in Perth.
Khawaja was dropped from the squad after the third Test in England and will be accompanying other Test hopefuls to fill in a number of batting slots up for grabs.
Joe Burns, Travis Head, Will Pucovski and Nic Maddinson will take part in the competitive race for finding a place in Australia's middle order.
"We will closely monitor performances in this match as well as the coming rounds of the Sheffield Shield before deciding upon our squad for the two-Test series against Pakistan," chief selector Trevor Hohns said.
Khawaja and Head have been appointed vice-captains for the practice game while Hohns suggested the selectors will be keenly viewing Carey's progress as a leader.
"This fixture represents an opportunity to provide Alex with more leadership experience and he will be supported by two experienced vice-captains in Usman Khawaja and Travis Head," Hohns said.
Rising star Pucovski was drafted into the Test squad for the home series against Sri Lanka but failed to get a chance to make his debut on the international stage.
His Victoria teammate Maddinson is also among the contenders eyeing a spot in the national side.
"Both are exciting batsmen whom we’ve had our eye on for some time," Hohns added.
Australia's four-pronged pace attack includes Jhye Richardson, who was unlucky to miss out on the World Cup following a shoulder injury.
He will be supported by Michael Neser, Sean Abbott and Riley Meredith, all of whom are yet to make their debut in Test cricket.
Pakistan will play three T20Is from November 3-8 before the first of the two Tests commences on November 21.
Alex Carey (c), Marcus Harris, Joe Burns, Usman Khawaja, Will Pucovski, Travis Head, Nic Maddinson, Michael Neser, Jhye Richardson, Sean Abbott, Riley Meredith