Saud Shakeel and Rohail Nazir will lead Pakistan Shaheens and Northern respectively for their matches against the Marylebone Cricket Club.
The MCC team, under the captaincy of Kumar Sangakkara, will travel to Lahore from 13 to 19 February during which they will play one 50-over fixture and three T20 games.
The 50-over match will take place against Pakistan Shaheens with 24-year-old Shakeel at the helm of the affairs.
The Karachi-born batting prodigy has been touted as a star for the future given his sparkling leadership credentials since he captained Pakistan to their ACC Emerging Teams Asia Cup 2019 title in November.
Several other youngsters have been rewarded for their prolific run in the domestic circuit by getting a spot in the 12-member squad.
Nadeem Khan, coordinator of the selection committee, said: “We have followed the policy of consistency and rewarding players for achieving success in Dhaka. There is only one change and that is of young Zeeshan Malik, who performed well in the Quaid-e-Azam Trophy, the last tournament of the 2019-20 domestic season to date.”
Current National T20 Cup champions Northern are without regular skipper Imad Wasim with 18-year-old Rohail chosen to lead the side in his absence.
Northern's 12-member line-up, selected by head coach Mohammad Wasim, also features Musa Khan, who was handed his maiden Test cap during Pakistan's tour of Australia.
Reiterating the significance of MCC's tour, PCB chief executive Wasim Khan said: “I can’t emphasise enough on the importance of the MCC’s tour to Pakistan, which will be their first in 48 years."
"The fact that the MCC side will be led by their president and one of the most respected cricketers, Kumar Sangakkara, reflects how the world’s oldest and most influential clubs, who are also the guardians of the Laws of Cricket, are viewing this tour," he added.
“The MCC’s tour of Pakistan is part of our sincere efforts and endeavours to resume regular and normal international cricket activities."
"Sri Lanka played a full series, while Bangladesh have just completed white-ball matches and are scheduled to return for the two Tests and an ODI. Similarly, recent visits by Cricket Australia, England and Wales Cricket Board, Cricket Ireland and the International Cricket Council officials are a testament of our untiring efforts.”
Saud Shakeel (c), Akif Javed, Haider Ali, Hasan Mohsin, Imran Rafiq, Mohammad Mohsin, Omair Bin Yousuf, Rohail Nazir (wk), Saif Badar, Sameen Gul, Umar Khan, Zeeshan Malik
Rohail Nazir (c & wk), Faizan Riaz (vc), Ali Imran, Haider Ali, Mubashir Khan, Musa Khan, Nauman Ali, Sarmad Bhatti, Shahzad Azam, Shiraz Khan, Zaid Alam, Zeeshan Malik