Moeen Ali survived a number of chances offered from his bat and utilized it tremendously to punish the Karachi Kings bowling attack.
His marvellous 42-ball 65 was embellished with nifty wristwork, regularly managing to find the boundary fence.
Moeen's remarkable poise was witnessed in the lofty drive off the bowling of Imad Wasim, when he elegantly picked the bones out of the tossed up delivery to launch it over extra cover.
Multan Sultans captain Shan Masood was finally among the runs as he superbly anchored his side's innings, powering them to an imposing total.
Although not known for boasting power-hitting abilities, Shan hit a solitary maximum in his fine knock that came off Mohammad Amir's rare error in line and length.
England pacer Chris Jordan has developed a reputation of being a canny customer in the death overs, often delivering the ball in the right channels drying up the flow of runs.
He nailed a dazzling yorker during Multan Sultans' innings to dismiss Shan as he aimed at the left-handed batsman's front foot.
The ball ended up ricocheting off his boot and crashed into the stumps while Shan was floored by the rapid pace.
Karachi Kings opener Babar Azam was undone by the extra pace and bounce from the lanky left-armer Mohammad Irfan, whose crucial breakthrough provided Multan Sultans with the impetus upfront.
Babar was unable to control his pull shot as the ball skied in the air and youngster Mohammad Ilyas rushed in to pull off an absolute blinder at deep square leg.
Shahid Afridi was guilty of shelling a straightforward chance when he spilled a lob from Alex Hales off Ilyas' bowling.
In the very next over, Afridi got his man as Hales found the fielder at point after going through with his shot a fraction too early.
Ravi Bopara held onto an excellent catch right on the cusp of Sultans' win as his grab sent Umaid Asif back into the pavilion.
Bopara did not let the ball evade his grasp despite a slight collision with Ilyas, that threatened to deviate his trajectory.
He claimed the catch on the rebound and allowed Sohail Tanvir to add another wicket to his tally.