Jason Roy has been rendered unavailable for the upcoming T20I series against Pakistan after suffering a left side strain.
The explosive opening batsman was hurt earlier this week during his side's preparation for the T20I clashes at Emirates Old Trafford.
He had to later undergo a scan on Wednesday, which confirmed his unfit status, though he will continue to remain with England's white-ball set-up.
Roy will commence his rehabilitation programme to recover in time for the ODI and T20I fixtures against the visiting Australian side next month, which starts at the Ageas Bowl on September 4.
England have not yet made it clear whether they will be roping in a replacement for the 30-year-old or not.
Roy's last T20 appearance came during the unfinished Pakistan Super League in March where he turned out for Quetta Gladiators.
He was part of England's ODI outfit in the series against Ireland but failed to score big across the three innings including two single-digit contributions.
Roy's absence may prompt the management to promote Tom Banton to the top of the order to open alongside the destructive Jonny Bairstow.
The first of England's three T20Is against Pakistan is scheduled to take place on August 28 with all matches set to held behind closed doors in Manchester.