Pakistan have named four uncapped players in their 15-man squad announced for the opening ODI against Zimbabwe on Friday in Rawalpindi.
Usman Qadir is yet to make his international debut while Khushdil Shah, Haris Rauf and Musa Khan have not received their maiden ODI cap.
Qadir's inclusion comes in the absence of Pakistan white-ball vice-captain Shadab Khan, who is suffering from stiffness in his upper leg following one of the intra-squad practice games before the series.
Qadir was a part of Pakistan's T20I squad for the Australia tour last year but could not get a game despite having the experience of playing in the Big Bash League.
Khushdil has featured in a solitary T20I for Pakistan whereas Rauf has appeared in five T20Is for the national side. Musa played a single Test and T20I in Australia in November 2019.
Among the notable omissions from the initial list of the 22 probables, Mohammad Hafeez has been left out from the final 15 while rising batting sensation Haider Ali will have to wait a bit longer to break into the ODI team.
The 50-over contest against Zimbabwe will mark Pakistan's first ODI in 12 months as they claimed a home series triumph over Sri Lanka under the leadership of former skipper Sarfaraz Ahmed in their previous ODI outing.
Sarfaraz has since been relieved of the captaincy responsibilities with Mohammad Rizwan drafted in his place as the designated wicketkeeper.
Faheem Ashraf has been recalled to the ODI set-up after being dropped from the 2019 World Cup squad, in order to add depth to the relatively inexperienced bowling resources.
Pakistan are currently ranked No. 6 in the ICC ODI rankings for teams with the outcome of the series affecting their standing in the inaugural World Cup Super League.
Babar Azam (capt), Imam ul Haq, Abid Ali, Fakhar Zaman, Haris Sohail, Mohammad Rizwan (wk), Iftikhar Ahmed, Khushdil Shah, Faheem Ashraf, Imad Wasim, Usman Qadir, Wahab Riaz, Shaheen Shah Afridi, Haris Rauf, Musa Khan