The lucrative T20 competition usually begins in March but had to be postponed to September owing to the coronavirus outbreak.
IPL 2020 was staged in the United Arab Emirates in the window freed up by the delayed T20 World Cup as the tournament ran across 54 days.
The Indian players then had to immediately undergo a two-week quarantine in Australia before preparing for the ODI series.
"It's really interesting how many injuries there have been throughout this summer," said Langer.
"We suffered through it during the white-ball series and [India] through the Test series.
"We'll review this, but I can't help think that the IPL this year probably wasn't ideal timing for anyone, certainly for such a big series like this."
David Warner and Marcus Stoinis were among the Aussie players injured during the white-ball portion of the international assignment whereas India have been particularly depleted by frequent fitness blows in the Test encounters.
Mohammed Shami, Umesh Yadav, KL Rahul and Ravindra Jadeja have already been ruled out of the series after Ishant Sharma and Bhuvneshwar Kumar were rendered unavailable for the tour.
Fitness doubts persist over Hanuma Vihari, Ravichandran Ashwin and Jasprit Bumrah for the final Test in Brisbane. Earlier, Rohit Sharma joined the Indian team midway through the Tests after nursing a hamstring niggle he sustained during the IPL.
"I love the IPL. I look at the IPL now like I used to look at [English] county cricket for young players, you go and play county cricket and it helps their development enormously," Langer commented.
"I think it's the same with the IPL with our players, it helps their white-ball development.
"But the timing of it ... probably wasn't ideal and I wonder if that's having an impact on the injuries we are seeing for both teams throughout this summer."